FAVIPIRAVIR

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Note: Favipiravir is a prescription antiviral medication. You must consult a qualified healthcare provider before use. The correct dosing and treatment duration depend on your health condition, age, and other medications. If you choose to buy favipiravir or favipiravir buy online, ensure it’s from a licensed pharmacy to guarantee safety and authenticity.

What is Favipiravir?

Favipiravir is an antiviral drug originally approved in Japan to treat flu cases resistant to typical treatments. It belongs to the class of RNA polymerase inhibitors and is taken orally. The drug requires prescription-only approval and is often stocked by governments in preparation for flu pandemics. It remains under study for treating other viruses like COVID-19 and Ebola, with varying degrees of evidence supporting its use.

How Does Favipiravir Work?

Favipiravir is a prodrug, meaning it’s inactive until broken down in the body into its active form, favipiravir-ribofuranosyl-5′-triphosphate (RTP). This active form blocks the RNA-dependent RNA polymerase (RdRp), an essential viral enzyme, and causes errors in viral RNA replication –  a process known as lethal mutagenesis.

Benefits of Favipiravir Treatment

Favipiravir has shown promise in several areas:

  • Influenza treatment: Approved in Japan for flu not responding to other antivirals. 
  • Wider antiviral activity: Lab studies suggest it may work against Ebola, Nipah, and other viruses. 
  • COVID-19 use: Authorized for emergency use in some countries (Russia, India, Thailand, etc.) based on early findings that suggest reduced symptoms and faster viral clearance. 
  • Ebola studies: Early trials in West Africa showed reduced death rates among patients with lower viral loads.

However, a recent Cochrane review found no clear evidence that favipiravir lowers death rates or hospitalization in COVID-19 patients.

Necessary Precautions

Before using favipiravir:

  • Not safe in pregnancy: Known to cause birth defects in animal studies- avoid if pregnant.
  • Consider kidney or liver function: The drug may affect organ systems and uric acid levels; monitoring may be needed.
  • Avoid if allergic: Stop if you experience any signs of severe reaction.
  • Alcohol: Effects are not well studied- best to avoid while on treatment.

FDA-Approved Medical Uses of Favipiravir

  • Influenza: Approved in Japan for pandemic flu stockpiling. 
  • COVID-19: Not FDA-approved in the U.S., but researchers have begun clinical trials under emergency protocols.
    Other countries like Russia, India, and Thailand have approved its use for mild to moderate COVID-19.

Side Effects

Common side effects include:

  • Nausea, vomiting, diarrhea
  • Raised uric acid levels
  • Decreased white blood cells, elevated liver enzymes 

Serious adverse reactions reported in monitoring databases involve the liver, kidneys, heart, and nervous system. Always tell your doctor if symptoms worsen or new ones appear.

Drug Interactions

Favipiravir may interact with medications processed by the liver. For example:

  • Pyrazinamide: Combined use can raise uric acid levels further. 
  • Other meds/supplements: Inform your doctor of all drugs and supplements to avoid harmful interactions.

FAQ

Favipiravir is an antiviral medication originally approved in Japan to treat influenza cases resistant to standard antivirals. It has also been studied for use against other viral infections such as Ebola, Nipah, and COVID-19.

Favipiravir is a prodrug that converts into its active form inside the body. The active compound blocks RNA-dependent RNA polymerase (RdRp), an enzyme viruses need to replicate.

Favipiravir should not be taken by pregnant women, as it can cause birth defects. People with serious kidney or liver problems, or those allergic to favipiravir, should avoid it unless prescribed by a doctor.

Serious reactions may affect the liver, kidneys, heart, or nervous system. Seek medical help if you experience unusual fatigue, jaundice, chest pain, confusion, or persistent stomach issues.

No. Favipiravir is generally prescribed for short-term antiviral treatment. Long-term safety has not been established and should only be considered under strict medical supervision.

Favipiravir is available in different strengths to suit varying treatment needs:  Feravir 200, 400 and 800 mg tablets.

Medical Disclaimer

This content is for educational purposes only. Always consult a licensed healthcare professional before starting or changing any medication. If you choose to buy favipiravir or favipiravir buy online, make sure it comes from a reputable pharmacy and is taken under medical supervision to guarantee safe and effective use.